Actress Christina Applegate, best known for her roles in Dead to Me and Married… with Children, has revealed that she has been hospitalized more than 30 times since being diagnosed with multiple sclerosis (MS) in 2021. The condition has deeply affected her health and continues to influence her daily life.
In a recent episode of her MeSsy podcast, which she co-hosts with fellow actress Jamie-Lynn Sigler, Applegate opened up about her most recent hospital stay. The episode was recorded directly from her hospital room, offering an unfiltered and deeply personal look at her ongoing battle with MS.
Applegate clarified that recording from the hospital wasn’t a planned media moment. “By the way, people out there, I’m not doing a podcast from the hospital because I felt like doing one from the hospital was an awesome idea,” she said. The recording had already been scheduled before her unexpected admission.
She went on to describe her current condition as “messy,” though she didn’t provide specific details about her symptoms or complications. Her candid tone and willingness to share even vague updates highlighted just how difficult and unpredictable her health journey has been.
Despite the challenges, Applegate remained optimistic. “But I’m going to be okay,” she told listeners—a simple yet powerful message of strength and perseverance. Her words offered comfort not only to herself but to others dealing with chronic illness.
Through her openness on the podcast, Applegate continues to inspire many. She uses the platform to shed light on the harsh realities of living with MS, while also creating a space for empathy, support, and honest conversation for those facing similar battles.